The results showed that 9 DEGs (ITGA2, SOS1, EGFR, MAPK1, PIK3R1, PTPN11, CD44, GAB2, TNIK) were simultaneously positively correlated with CALCR expression, and were associated with shorter overall survival in renal clear cell carcinoma patients (Figure 4B). Here, PIK3R1 is linked to clear cell renal carcinoma.