The results showed that 9 DEGs (ITGA2, SOS1, EGFR, MAPK1, PIK3R1, PTPN11, CD44, GAB2, TNIK) were simultaneously positively correlated with CALCR expression, and were associated with shorter overall survival in renal clear cell carcinoma patients (Figure 4B). This evidence concerns the gene PTPN11 and clear cell renal carcinoma.