The results showed that 9 DEGs (ITGA2, SOS1, EGFR, MAPK1, PIK3R1, PTPN11, CD44, GAB2, TNIK) were simultaneously positively correlated with CALCR expression, and were associated with shorter overall survival in renal clear cell carcinoma patients (Figure 4B). Here, TNIK is linked to clear cell renal carcinoma.