Although over 80 potential causes for laminitis have been proposed (Heymering, 2010), there are considered to be three main forms of laminitis, namely sepsis‐associated laminitis that occurs secondary to SIRS and/or sepsis, supporting limb laminitis that occurs in horses with severe lameness in the contralateral limb, and endocrinopathic laminitis that encompasses laminitis associated with insulin dysregulation (ID; Patterson‐Kane et al., 2018). This evidence concerns the gene INS and Sepsis.