Cooperative upregulation of ICAM1 gene transcription by ETS-1 and autoimmune regulator (AIRE) in human oral squamous cell carcinoma cells, and by ETS-1 and signal transducer and activator of transcription 1 (STAT 1) in human HEK293 and monkey COS-1 kidney cell lines are also reported (12, 13). The gene discussed is ETS1; the disease is oral cavity squamous cell carcinoma.