NPPB and heart failure: BNP and NT-proBNP are hormones secreted under the stimulation of factors such as cardiomyocyte stretching, neurohormone activation and myocardial hypoxia, which can act on distant tissues and have the effects of diuresis, vasodilation and regulation of the body’s water and sodium balance, both of which are widely used as clinical markers of heart failure and can also be applied in the monitoring of chemotherapy-induced left ventricular dysfunction.