The enhanced expression of several genes whose roles were revealed within the apoptosis pathway in the present study of gibel carp was previously found in Nile tilapia (Oreochromis niloticus) infected by tilapia lake virus; these genes were, specifically, nfkbia within the nfkbia pathway, and socs within the JAK-STAT pathway, suggesting that the virus was able to successfully establish infection by subverting the host’s immune response. The gene discussed is CISH; the disease is infection.