Toll-like receptor activity patterns have been globally studied considering immune biomarkers in breast tumors in a multicentric proteome study (105) with a clear clinical goal, but comprehensive basic studies have also been performed in relation to the activity of cancer-associated fibroblasts’ presence and absence (106), immune escape by GATA3 destabilization (107), and follicular helper cells as promoters of effective adaptive immunity (108). This evidence concerns the gene GATA3 and cancer.