HDAC6 and familial dilated cardiomyopathy: For instance, whole-body KD of HDAC3, HDAC4, or HDAC6 was shown to be protective against ischemic injury, vascular inflammation, or DCM, respectively (Yang et al., 2018; Na et al., 2021; Qiu et al., 2021; Pang et al., 2022).