IL13RA1 and allergic disease: Rothenberg et al. (2011) showed that eosinophil recruitment and chemokine production critically depend on IL-13Rα1 (receptor for IL-13 induction) and IL-13 signaling after Aspergillus sensitization.In the present study, the challenge posed by A. fumigatus conidia in A549 cells regulated the expression of IL-13, showing that the importance of this cytokine in inducing allergic reactions and that only higher doses of S. boulardii CW could downregulate its expression.