Similarly, a cohort of 126 patients with CNV and 120 patients with polypoidal choroidal vasculopathy (PCV) was compared to 274 healthy controls, and no significant association between the TLR3-rs3775291 polymorphism and CNV in AMD was found genotypic p = 0.698, allelic = 0.5847) (133). This evidence concerns the gene TLR3 and Polypoidal choroidal vasculopathy.