CXCL10 and Keratoconjunctivitis sicca: For example, in dry eye mouse models, bacterial lipopolysaccharides (LPS) increases the expression of inflammatory mediators including IL-1β, IL-6, CXCL10, IL-12a, and IFN-γ in the conjunctiva and IL-1β and CXCL10 in the cornea (83).