From the three sorted populations harvested from PBMC cultures, all T2DM-derived myeloid populations (i.e. CD14+CD105–CD133– (CD14+DN) and CD14+CD105+CD133+ (CD14+DP PAC)), increased REC in vitro tubule formation as compared to control lo-GF cultures without cells added, although addition of CD14+DP cells from NoDR patients did not reach statistical significance (Figure 2). The gene discussed is ENG; the disease is type 2 diabetes mellitus.