However, serum ARAs, immunoglobulin G (IgG) against whole human retina extract (WHRE) and interphotoreceptor retinoid-binding protein (IRBP) were also detected at a higher level in cases of ocular toxoplasmosis and other non-infectious, immune-mediated uveitis (23). The gene discussed is RBP3; the disease is ocular toxoplasmosis.