STAT3 and neoplasm: Strikingly, the combination of HLX02 and HLX11 dramatically increased STAT3 (Y705), P70 S6 (T421/S424), and AKT1/2/3 (S473) phosphorylation levels, which potentially promoted tumor cell proliferation, anti-apoptosis and drug resistance in NCI-N87 gastric cancer cells.