Similar to other tumour cell lines,4 GSDMB was upregulated markedly under stimulation of interferon‐γ (IFN‐γ), and cleaved into the p30 fragment in response to electroporation of purified GrzA in Caco‐2 and HT‐29 cells, the human adenocarcinoma colorectal cell lines, accompanied by significantly increased lactate dehydrogenase (LDH) activity (Supplementary Figure 1A–E). Here, GSDMB is linked to neoplasm.