Additionally, the ChIP-seq data and RNA-seq data from public databases (GSE138295, GSE126739) revealed that c-Myc has a significant signal in the promoter region of PFKP (Supplementary Fig. 6B), and the PFKP mRNA levels were significantly reduced after reduction of c-Myc in lymphoma cells (Supplementary Fig. 6C). The gene discussed is MYC; the disease is lymphoma.