Multivariate and ROC analyses revealed the predictive value for 1-year all-cause mortality as a multifactorial model including clinical factors (diabetes mellitus and atrial fibrillation) followed by laboratory parameters (lymphocyte count, Rbc, LDH and Il-6), yielding a sensitivity of 65.2% and specificity of 90.8% and an area under the curve (AUC) of 0.897, as shown in MODEL 1 in Fig. 1. This evidence concerns the gene IL6 and atrial fibrillation.