IDH2 and central nervous system cancer: For instance, IDH mutant (IDHmut) gliomas with 1p/19q codeletion often signal a better prognosis [11, 12], and the co-occurrence of IDH and TERT promoter mutations in oligodendrogliomas correlates with an improved survival rate, unlike the prognosis for tumors with TERT mutations (TERTmut) but without IDH mutations [10–12].