The enzyme-linked immunosorbent assay results for the seven autoantibodies (P53, PGP9.5, SOX2, GAGE7, GBU4-5, MAGE, and CACE) of lung cancer showed increased levels of P53 (30.8 U/mL; normal range: 0–13.1 U/mL), PGP9.5 (18.4 U/mL; normal range: 0–11.1 U/mL), SOX2 (18.0 U/mL; normal range: 0–10.3 U/mL), and GBU4-5 (9.6 U/mL; normal range: 0–7.0 U/mL). This evidence concerns the gene SOX2 and lung carcinoma.