Other parameters which distinguished hemolytic from malproductive anemia in LGLL included a lower median Hb nadir, g/dL (7.3 vs. 10.7, p < 0.0001), higher median reticulocyte count %/index (4/1.9 vs. 1.1/0.6) and higher LDH, U/L (345 vs.198) (Fig. 1). This evidence concerns the gene GSTM1 and anemia (phenotype).