CDK4 and neoplasm: The CDK4 gene was amplified in 4 samples (BRAF WT (N = 1), BRAFV600E (N = 1), N/A (N = 2)), and in 1 of these, CDK4 amplification was accompanied by amplification of CDKN2A and CDKN2B. No correlation between specific tumor type, location or BRAF status was observed.