E2F1 and melanoma: When searching these genes in the GDC (Genomic Data Commons) data portal of National Cancer Institute54, in project ID: TCGA-SKCM where they identified CNV in 467 melanoma samples, deletion predominated and was detected in 50.54% of samples for gene KIF25 and in 48.39% samples for gene DIP2C. Predominantly, gain of gene E2F1 was detected in 38.54% samples and in case of TFG, gain was captured in 13.92% and loss in 14.56% of melanoma samples.