Based on the TIMER database, the results demonstrated that GPC-1 expression was significantly associated with the abundance of infiltrating immune cells: CD8+ T cells in 15 types of cancer, CD4+ T cells in 17 types of cancer, neutrophils in 19 types of cancer, myeloid dendritic cell in 18 types of cancer, macrophages in 16 types of cancer and B cells in 14 types of cancer (Fig. 4A). This evidence concerns the gene CD4 and cancer.