Subsequently, we confirmed that IDH1-mutant gliomas demonstrated a more favorable outcome than IDH1 wild type in our cohort, 916 cases from the Chinese Glioma Genome Atlas (CGGA) and 868 cases from The Cancer Genome Atlas (TCGA) databases (detailed information is provided in Figs. 1B–D and S1A–F). Here, IDH1 is linked to central nervous system cancer.