FERMT1 and hepatocellular carcinoma: TCGA analysis of FERMT1 RNA expression levels revealed overexpression compared to normal samples (log RNA Seq Vs RSEM, Z-score threshold +/− 2.0) in lung, colorectal cholangiocarcinoma and hepatocellular carcinoma suggestive of potential oncogenic roles in these tumor types whilst a preponderance of downregulation of expression is observed in thyroid, kidney, breast, endometrial and prostate tumors indicating potential tumor suppressor roles in these tumor types (Supplementary Fig. 1C).