HOTAIR and cancer: HOTAIR has been identified as a key player in various cancers, including breast cancer (Sørensen et al. 2013), hepatocellular carcinoma (Yang et al. 2011; Ishibashi et al. 2013), colorectal cancer (Kogo et al. 2011; Wu et al. 2014a, b), ovarian cancer (Li et al. 2015; Dai et al. 2021), and lung cancer (Ono et al. 2014; Liu et al. 2013).