ACTC1 and dilated cardiomyopathy: Hypertrophic and dilated cardiomyopathy causing mutations have been detected mostly in genes of sarcomere proteins such as Mybpc2, Myh7, Tnnt2, Tnnc1, Tnni3, Tpm1, Ttn, Actc1, Myl2, and Myl3 (van der Velden & Stienen, 2019).