To further confirm the mechanism of TUG1 in regulating antitumor immunity, we downregulated TUG1 in human liver cancer HepG2 cells and found that both miR‐340 and miR‐141 were upregulated in TUG1‐downregulated cells (Figure 6A), while the expressions of PD‐L1 and CD47 decreased (Figure 6B). The gene discussed is CD274; the disease is liver cancer.