In another study that investigated the underlying cause of Birdshot Uveitis, an autoimmune disease associated with ERAP2 haplotype A [46], the authors found that ERAP2 haplotype A generates an HLA-A29-specific antigen repertoire by increasing the abundance of a distinct motif (with F and Y amino acids at P2) [14]. Here, ERAP2 is linked to autoimmune disease.