EGCG effected marked decreases in fibroblast (periostin, sFRP2) and epithelial (KRT17) genes that are upregulated in IPF as well as increased surfactant protein C (SFTPC) expression (Figure 4, F and G, and Supplemental Figure 5C). This evidence concerns the gene SFRP2 and idiopathic pulmonary fibrosis.