Both the formulations of TPE microcapsules (alone and with probiotics combination), demonstrated a protective action against enterocolitis by reduction of inflammation and oxidative stress, as indicated by the decreased intestinal and stomach malondialdehyde (MDA), interleukin 6 (IL-6), interleukin 1 beta (IL-1β), tumour necrosis factor alpha (TNF-α), and nitric oxide (NO) levels and increased superoxide dismutase (SOD), catalase (CAT), and reduced glutathione (GSH) levels. Here, IL6 is linked to enterocolitis.