C1QTNF1 and rheumatoid arthritis: MR analyses revealed negative causal inferences for complement C1q tumor necrosis factor-related protein 1 (CTRP1) (OR = 0.9999, 95% CI: 0.99984–0.999986, PBH = 1.10×10-275) and tumor necrosis factor-inducible gene 6 protein (OR = 0.9996, 95% CI: 0.99958–0.99963, PBH = 2.24×10-228) with RA (Figure 3B; Supplementary Table 4).