In the present study, the levels of systemic inflammatory indicators were significantly correlated with hepatic steatosis, and there were both linear and nonlinear relationships between those indicators and NAFLD: a nonlinear positive correlation of CRP, a linear positive correlation of monocyte count and neutrophil count, a nonlinear U-shaped correlation of NLR, PLR, and SII, and a nonlinear L-shaped correlation of lymphocyte count and LMR. This evidence concerns the gene CRP and metabolic dysfunction-associated steatotic liver disease.