NFKB1 and nonpapillary renal cell carcinoma: Importantly, ZHX2 or p65 overexpression significantly rescued ccRCC cell growth and NF-κB target gene expression after XMU-MP-1 treatment (Fig. 6A–F), lending further support that YAP inhibits ccRCC cancer cell growth by opposing the cooperativity between p65 and ZHX2.