Additionally, we tested two PY-NLS’s, UL79 and HNRNP A1, and found that HNRNP A1 conferred CPSF6–358 nuclear localization and supported HIV-1 infection similarly as CPSF6-FL, while UL79 failed to rescue both CPSF6–358 nuclear localization and HIV-1 infection (Table 1). The gene discussed is CPSF6; the disease is HIV-1 infection.