Network pharmacological results showed that the main active ingredients in BHP PM-SS, such as Puerarin, Daidzin, Daidzein, Schisantherin A, Schisandrin A, Schisandrin C, Schisandrin B, Schisandrol A and Schisandrol B, can regulate the Pathways in cancer, PI3K-AKT signaling pathway and MAPK signaling pathway by acting on the targets of AKT1, TNF, EGFR, JUN, HSP90AA1, and STAT3, thereby ameliorating the “jaundice”, “abdominal distension”, “fatigue”, “CINV” and “poor appetite” associated with ALI. This evidence concerns the gene AKT1 and cancer.