SOD2 and hydrops fetalis: A study showed that Sini decoction reduced lipid peroxidation incidence in myocardial mitochondria by increasing levels of antioxidant enzymes (copper-zinc superoxide dismutase and manganese superoxide dismutase, Mn-SOD (Zhao et al., 2005)) and decreasing malondialdehyde level, further protecting mitochondrial membrane integrity and reducing HF incidence (Zhao et al., 2010).