Nonetheless, our discovery results confirmed a number of previously described multiple sclerosis-specific markers [multiple sclerosis patients versus controls; CXCL13, CD27, IL12, CD5, C-C motif chemokine 3 (CCL3) (also known as macrophage inflammatory protein 1-alpha (MIP1-alpha)), CXCL11, CXCL10, IL7 and tumour necrosis factor ligand superfamily member 14 (TNFSF14)].24-26 These nine proteins are consistent with previous studies. Here, CD27 is linked to multiple sclerosis.