CHAT and tauopathy: The coexistence of tauopathy in BF within selected ChAT+ cell clusters of cholinergic nuclei was observed occasionally in BF of 3xTgAD mice, including the SI (substantia innominata), nBM (nucleus Basalis of Meynert), and HDB (nucleus of horizontal limb diagonal band of Broca) on regions of interest (ROI, indicated by circle) at sagittal brain sections (Fig. 4A–G).