TET2 and diabetes mellitus: Furthermore, the stability of circRNA YTHDC2 is regulated via YTHDC2-mediated m6A modification; subsequently, circRNA YTHDC2 is verified to inhibit the expression of ten-eleven translocation 2 (TET2), a regulator of DNA demethylation, which prompts a dedifferentiated phenotype in vascular smooth muscle cells, contributing to diabetic vascular complications (10).