Chronic exposure to stress, including adolescent stress, chronic unpredictable mild stress (CUMS), CRS, and chronic social defeated stress (CSDS), reduces synaptic plasticity markers and dendritic spine density.[43, 44] In our study, no significant differences were observed in postsynaptic density protein 95 (PSD95) protein levels in the mPFC in any group. The gene discussed is DLG4; the disease is congenital rubella syndrome.