Rare follicular lymphomas have concurrent MYC and BCL2 rearrangements.(37–39) These follicular lymphomas may on average be of higher histologic grade and have somewhat more aggressive behavior than unselected follicular lymphomas, but they are less aggressive than HGBCL or DLBCL with concurrent MYC and BCL2 rearrangement and are not included in this diagnostic category in WHO-HAEM4R, WHO-HAEM5, or ICC. This evidence concerns the gene MYC and intrahepatic cholangiocarcinoma.