However, since refractory celiac disease type II (RCD II) shows intraepithelial lymphocytes that often have an abnormal TCR-silent phenotype, typically are monoclonal, usually harbor somatic mutations in JAK/STAT pathway genes, and have a high risk for lymphoma development, the ICC includes RCD II in the classification under EATL.(82–84) Monomorphic epitheliotropic intestinal T-cell lymphoma and intestinal T-cell lymphoma, NOS remain unchanged in both the ICC and WHO-HAEM5. This evidence concerns the gene SOAT1 and enteropathy-associated T-cell lymphoma.