Both WHO-HAEM5 and ICC recognize the same three subtypes: angioimmunoblastic type, follicular type and an NOS category for nodal PTCLs that are found to have a T follicular helper (Tfh) phenotype as defined by 2 or more Tfh markers (such as PD1, ICOS, CXCL13, CD10, BCL6, CXCR5), but without the distinctive features of the other two types. The gene discussed is BCL6; the disease is intrahepatic cholangiocarcinoma.