This profile was more marked in patients with AKI at D5-7, who presented with quantitative (higher plasmatic IL-10 concentration, higher percentage of immature CD10lowCD16low immature neutrophils, lower monocyte Human Leucocyte Antigen-DR expression, lower CD3D and CD127 mRNA expressions) and qualitative (lower TNF-α production after LPS stimulation and lower IFN-γ production after SEB stimulation) alterations of their immune system. Here, CD3D is linked to acute kidney injury.