Serum MMP-7 holds great promise for diagnosing BA with AUCs all > 0.9 [14–16, 18, 20–24], superior to other diagnostic methods including GGT and ultrasound, however, optimal cutoff values proposed varied significantly across these studies (52.85 ng/mL by Yang et al. [14]. The gene discussed is MMP7; the disease is breast angiosarcoma.