In the retrospective cohort, the median serum MMP-7 level was higher in the BA group than that in the non-BA group (56.87 ng/mL (IQR: 32.64, 89.42) vs. 9.40 ng/mL (IQR: 7.30, 12.00); P < 0.001). Here, MMP7 is linked to breast angiosarcoma.