A significant increase in serum concentrations of inflammatory-related indicators such as hypersensitive C-reactive protein (hs-CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) was observed in AF patients, with the degree of such increase being proportional to the prognosis of these patients and being capable of predicting the recurrence rate of AF following catheter ablation surgery [3]. The gene discussed is TNF; the disease is atrial fibrillation.