Samples with a value greater than or equal to the median were classified as “NRP1-high,” while those below the median were classified as “NRP1-low.” To investigate the relationship between NRP1 expression and the estimated GFR (eGFR), we analyzed medical records of these 217 patients, including data on gender, age, history of hypertension and diabetes, blood routine, blood biochemistry, urine routine and the eGFR (Table S1). Here, NRP1 is linked to Hypertension.