TNFSF12 and hypertensive disorder: Our two-sample MR analysis of druggable genes and exposures using the same parametric criteria showed that TNFSF12 was significantly associated with hypertension (OR = 1.006; 95% CI, 1.002–1.011; P = 6.90 × 10−3), which remained significant after FDR correction (IA: Pfdr = 1.38 × 10−2; SAH: Pfdr = 2.01 × 10−2).