Regenerating islet-derived family member IV (Reg IV), a member of the calcium-dependent lectin gene superfamily, has been associated with tumor cell invasion and migration in various cancers, including colorectal, gastric, gallbladder, pancreatic, ovarian, prostate, and lung cancers, demonstrating a correlation with unfavorable prognosis and clinicopathological characteristics [8, 9]. This evidence concerns the gene REG4 and neoplasm.