Further, the expression levels of BRD4 in the liver increased along with the progression of MASH liver pathology, according to the Pearson correlation analysis of BRD4 positivity in liver tissue and NAS score in each patient, revealing a positive linear correlation between BRD4 positivity and NAS score (R2 = 0.8972, p < 0.0001) (Fig. 6F). The gene discussed is BRD4; the disease is metabolic dysfunction-associated steatohepatitis.