PRKCD and Anxiety: Within CeA, a functional role of PKCδ+ neurons was initially described in fear conditioning, anxiety-related behaviors, and appetite regulation (Ciocchi et al., 2010; Haubensak et al., 2010; Douglass et al., 2017), while more recent work by our group and others has implied this neuronal population in addiction-related behaviors (Venniro et al., 2018; Venniro and Shaham, 2020; Domi et al., 2021; Dilly et al., 2022).