CLN2-disease natural history has been characterized using functional scales, typically either Hamburg (modified to CLN2-Disease Rating Scale) or Weill-Cornell, which focus on seizures, ambulation, language, and visual function.2,4,6 Some movement disorders are well-recognized: ataxia is an early hallmark contributing to loss of ambulation; myoclonus is almost universal representing both epileptic and nonepileptic movements.2 Other movement disorders such as chorea, tremor, and dystonia are less well characterized. This evidence concerns the gene TPP1 and Dystonia.