salvianolic acid B inhibits activation of NF-κB pathway by inhibiting the phosphorylation of p65 (151), alleviating inflammation of arthritis mouse, it can also reduce the release of TNF-α, IL-1β, and IL-6 by inhibiting nuclear translocation of p65 producing anti-atherosclerotic effect (152). The gene discussed is NFKB1; the disease is Arthritis.